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Article

RNA editing generates tissue-specific sodium channels with distinct gating properties.

The Journal of biological chemistry - 30 Jul 2004

Song Weizhong, Liu Zhiqi, Tan Jianguo, Nomura Yoshiko, Dong Ke

Abstract excerpt

Sodium channels play an essential role in generating the action potential in eukaryotic cells, and their transcripts, especially those in insects, undergo extensive A-to-I RNA editing. The functional consequences of RNA editing of sodium channel transcripts, however, have yet to be determined. We characterized 20 splice variants of the German cockroach sodium channel gene BgNa(v). Functional analysis revealed...

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Identifiers

PMID: 15136570
DOI: 10.1074/jbc.M402392200
PMCID: PMC3066004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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