Article
Development of skeletal muscle sodium and potassium currents in zebrafish sofa potato mutants.
Developmental neuroscience - 1 Jan 2009
Coutts Christopher A, Cunningham Marcus E, Ali Declan W
Abstract excerpt
In some cells, the development of voltage-gated channels requires synaptic input, while in others it does not. Here we investigate whether the sodium and potassium currents in the skeletal muscle of zebrafish sofa potato (sop(-/-)) mutants develop normally. Zebrafish sop(-/-) mutants do not express nicotinic acetylcholine receptors at neuromuscular junctions, and therefore do not exhibit synaptic activity in...
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