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Article

K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve.

Journal of neurocytology - 1 Jan 2000

Rasband M N, Trimmer J S, Peles E, Levinson S R, Shrager P

Abstract excerpt

The localization of Shaker-type K(+) channels in specialized domains of myelinated central nervous system axons was studied during development of the optic nerve. In adult rats Kv1.1, Kv1.2, Kv1.6, and the cytoplasmic beta-subunit Kvbeta2 were colocalized in juxtaparanodal zones. During development, clustering of K(+) channels lagged behind that for nodal Na(+) channels by about 5 days. In contrast to the PNS,...

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Source

Identifiers

PMID: 10739574
DOI: 10.1023/a:1007057512576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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