Deletion of voltage-gated channel affects glomerular refinement and odorant receptor expression in the mouse olfactory system.

Abstract excerpt

Olfactory sensory neurons (OSNs) expressing a specific odorant receptor (OR) gene send axonal projections to specific glomeruli, creating a stereotypic olfactory sensory map. Odorant receptor sequence, G-protein cAMP signaling, and axon guidance molecules have been shown to direct axons of OSNs toward central targets in the olfactory bulb (OB). Although the OR sequence may act as one determinant, our objective...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Axons
• Share to Galactosides
• Share to GTP-Binding Proteins