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Article

Alterations of DNA mismatch repair proteins and microsatellite instability levels in gastric cancer cell lines.

Laboratory investigation; a journal of technical methods and pathology - 1 Jul 2004

Yao Yuan, Tao Hong, Kim Jae J, Burkhead Benjamin, Carloni Emilia, Gasbarrini Antonio, Sepulveda Antonia R

Abstract excerpt

Alterations in DNA mismatch repair (MMR) proteins result in microsatellite instability (MSI), increased mutation accumulation at target genes and cancer development. About one-third of gastric cancers display high-level microsatellite instability (MSI-High) and low-level microsatellite instability (MSI-Low) is frequently detected. To determine whether variations in the levels of MMR proteins or mutations in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15133479
DOI: 10.1038/labinvest.3700117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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