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Article

Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy.

Blood - 15 May 2005

Tan Peng H, Beutelspacher Sven C, Xue Shao-An, Wang Yao-He, Mitchell Peter, McAlister James C, Larkin D Frank P, McClure Myra O, Stauss Hans J, Ritter Mary A, Lombardi Giovanna, George Andrew J T

Abstract excerpt

Genetic modification of dendritic-cell (DC) function is an attractive approach to treat disease, either using mature DCs (mDCs) to immunize patients, or immature DCs (iDCs) to induce tolerance. Viral vectors are efficient at transducing DCs, and we have investigated the effect of transduction with a variety of viral vectors on the phenotype and function of DCs. Adenovirus (Ad), human immunodeficiency virus (HIV),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15671441
DOI: 10.1182/blood-2004-10-3880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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