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Article

Breaking Entry-and Species Barriers: LentiBOOST® Plus Polybrene Enhances Transduction Efficacy of Dendritic Cells and Monocytes by Adenovirus 5.

Viruses - 5 Jan 2022

Strack Astrid, Deinzer Andrea, Thirion Christian, Schrödel Silke, Dörrie Jan, Sauerer Tatjana, Steinkasserer Alexander, Knippertz Ilka

Abstract excerpt

Due to their ability to trigger strong immune responses, adenoviruses (HAdVs) in general and the serotype5 (HAdV-5) in particular are amongst the most popular viral vectors in research and clinical application. However, efficient transduction using HAdV-5 is predominantly achieved in coxsackie and adenovirus receptor (CAR)-positive cells. In the present study, we used the transduction enhancer LentiBOOST®...

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Share to Adenoviruses, Human
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphocyte Culture Test, Mixed

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Source

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Identifiers

PMID: 35062296
DOI: 10.3390/v14010092
PMCID: PMC8781300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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