Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Innate Immune Response to Viral Vectors in Gene Therapy

24 Aug 2023

Abstract excerpt

Viral vectors play a pivotal role in the field of gene therapy, with several related drugs having already gained clinical approval from the EMA and FDA. However, numerous viral gene therapy vectors are currently undergoing pre-clinical research or participating in clinical trials. Despite advancements, the innate response remains a significant barrier impeding the clinical development of viral gene therapy. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to interferon and immune responses
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37766208
DOI: 10.3390/v15091801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Innate Immune Response to Viral Vectors in Gene TherapyPMID 37766208Read ↗

The Challenge for Gene Therapy: Innate Immune Response to AdenovirusesSemantic proximity Read ↗

The Innate Immune Response to Adenovirus VectorsSemantic proximity Read ↗

Innate Immune Sensing of Adeno-Associated Virus VectorsSemantic proximity Read ↗

Advances of Recombinant Adenoviral Vectors in Preclinical and Clinical ApplicationsSemantic proximity Read ↗

Viral Vectors Engineered for Gene TherapySemantic proximity Read ↗

The induction of inflammation by adenovirus vectors used for gene therapySemantic proximity Read ↗

Viral vector platforms within the gene therapy landscapeSemantic proximity Read ↗

Innate immunity to adenovirus: lessons from miceSemantic proximity Read ↗

Significance of Preexisting Vector Immunity and Activation of Innate Responses for Adenoviral Vector-Based TherapySemantic proximity Read ↗

Viral gene delivery vectors: the next generation medicines for immune-related diseasesSemantic proximity Read ↗

Construction and application of adenoviral vectorsSemantic proximity Read ↗

Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral VectorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.