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Breaking Entry- and Species Barriers: LentiBOOST® Plus Polybrene Enables High Transduction Efficacy of Dendritic Cells and Monocytes by Adenovirus 5

2021-08-09

Abstract excerpt

Due to their ability to trigger strong immune responses, adenoviruses (HAdVs) in general and the serotype5 (HAdV5) in particular are amongst the most popular viral vectors in research and clinical application. However, efficient transduction using HAdV5 is predominantly achieved in coxsackie and adenovirus receptor (CAR)-positive human cells. In the present study, we used the transduction enhancer LentiBOOST® comp...

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Literature Corpus work: 8b05756f-b36a-5f33-822f-2dfb1b404127
DOI: 10.21203/rs.3.rs-701427/v1

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