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Article

Gender and plasma iron biomarkers, but not HFE gene mutations, increase the risk of colorectal cancer and polyps.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2015

Castiella Agustin, Múgica Fernando, Zapata Eva, Zubiaurre Leire, Iribarren Arantxa, de Juan M Dolores, Alzate Luis, Gil Ines, Urdapilleta Gregorio, Otazua Pedro, Emparanza José Ignacio

Abstract excerpt

A cohort study of patients included in the Basque Country colorectal cancer (CRC) screening programme was carried out to assess the risk of adenomatous polyps and CRC (P-CRC) associated with HFE gene mutations, with gender and with iron biomarkers (serum ferritin (SF), iron (Fe) and transferrin saturation index (TSI)). Among 432 included patients (mean age 59.8 years), 263 were men (60.9 %) and 169 women (39.1...

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Share to Adenomatous Polyps
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25854174
DOI: 10.1007/s13277-015-3406-2

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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