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Article

A single point mutation of the influenza C virus glycoprotein (HEF) changes the viral receptor-binding activity.

Virology - 1 May 1992

Szepanski S, Gross H J, Brossmer R, Klenk H D, Herrler G

Abstract excerpt

From strain JHB/1/66 of influenza C virus a mutant was derived with a change in the cell tropism. The mutant was able to grow in a subline of Madin-Darby canine kidney cells (MDCK II) which is resistant to infection by the parent virus due to a lack of receptors. Inactivation of cellular receptors by either neuraminidase or acetylesterase and generation of receptors by resialylation of cells with...

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Identifiers

PMID: 1566586
DOI: 10.1016/0042-6822(92)90737-a
PMCID: PMC7131248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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