Article
Persistent influenza C virus possesses distinct functional properties due to a modified HEF glycoprotein.
The Journal of general virology - 1 Sept 1994
Marschall M, Herrler G, Böswald C, Foerst G, Meier-Ewert H
Abstract excerpt
A model of long term viral persistence has been established by selecting a spontaneous mutant strain of influenza C/Ann Arbor/1/50 virus in a permanent carrier culture of MDCK cells. Infectivity and cell tropism are mainly determined by the multifunctional viral membrane glycoprotein (HEF). HEF analysis was aimed at identifying a putative correlation between sequence and function, i.e. receptor binding, enzymatic...
Topics
- Animals
- Antibodies, Monoclonal
- Base Sequence
- Cell Line
- Chick Embryo
- Chickens
- DNA Primers
- Dogs
- Epitopes
- Erythrocytes
- Fibroblasts
- Genetic Variation
