Article

Influenza A virus agnostic receptor tropism revealed using a novel biological system with terminal sialic acid-knockout cells

2022-02-21

Abstract excerpt

Avian or human influenza A viruses bind preferentially to avian- or human-type sialic acid receptors, respectively, indicating that receptor tropism is an important factor for determining the viral host range. However, there are currently no reliable methods for analyzing receptor tropism biologically under physiological conditions. Here, we established a novel system using MDCK cells with avian- or human-type sia...

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Literature Corpus work: 969fdf9e-4eee-5097-bd69-7eab89170570
DOI: 10.1101/2022.02.21.481323

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