Replication of DHBV genomes with mutations at the sites of initiation of minus- and plus-strand DNA synthesis.

doi:10.1016/0042-6822(92)90751-a

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Article

Replication of DHBV genomes with mutations at the sites of initiation of minus- and plus-strand DNA synthesis.

Virology - 1 May 1992

Condreay L D, Wu T T, Aldrich C E, Delaney M A, Summers J, Seeger C, Mason W S

Abstract excerpt

We have examined the consequences on duck hepatitis B virus DNA synthesis of deleting the 5' and 3' copies of the 12 base sequence, DR1, from the viral pregenome. With the wild-type virus, reverse transcription initiates at nt 2537 within the 3' copy of DR1. When this sequence was deleted, initia...

Topics

Animals
Base Sequence
Chickens
Cloning, Molecular
DNA Replication
DNA, Viral
Genome, Viral
Hepatitis B Virus, Duck
Molecular Sequence Data
Mutation
Transcription, Genetic
Transfection
Tumor Cells, Cultured

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