Article
Restoration in vivo of defective hepatitis delta virus RNA genomes.
RNA (New York, N.Y.) - 1 Jun 2006
Gudima Severin O, Chang Jinhong, Taylor John M
Abstract excerpt
The 1679-nt single-stranded RNA genome of hepatitis delta virus (HDV) is circular in conformation. It is able to fold into an unbranched rodlike structure via intramolecular base-pairing. This RNA is replicated by host RNA polymerase II (Pol II). Such transcription is unique, because Pol II is known only for its ability to act on DNA templates. The present study addressed the ability of the HDV RNA replication to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
