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Article

Werner helicase polymorphism is not associated with Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Dec 2004

Payão Spencer Luiz Marques, de Labio Roger Willian, Gatti Luciano Lobo, Rigolin Valdeci O S, Bertolucci Paulo H F, Smith Marília de A C

Abstract excerpt

Alzheimer disease (AD) is the most common neurodegenerative disorder in the elderly and is also considered a progeroid genetic syndrome. The etiology of AD is complex and the mechanisms underlying its pathophysiology remains to be clarified. Werner syndrome (WS) is a rare autosomal recessive disorder characterized as a segmental progeroid syndrome. The gene (WRN) was recently identified. Its product acts as a DNA...

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Source

Identifiers

PMID: 15665399
DOI: 10.3233/jad-2004-6603

Genes

WRN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Werner helicase polymorphism is not associated with Alzheimer's disease.PMID 15665399Read ↗

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Single nucleotide polymorphisms in base-excision repair genes hOGG1, APE1 and XRCC1 do not alter risk of Alzheimer's disease.Semantic proximity Read ↗

Impact of genetic variations in the WRN gene on age related pathologies and mortality.Semantic proximity Read ↗

Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis.Semantic proximity Read ↗

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