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Article

Frequency of Werner helicase 1367 polymorphism and age-related morbidity in an elderly Brazilian population.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jul 2005

Smith M A C, Silva M D A, Araujo L Q, Ramos L R, Labio R W, Burbano R R, Peres C A, Andreoli S B, Payão S L M, Cendoroglo M S

Abstract excerpt

Werner syndrome (WS) is a premature aging disease caused by a mutation in the WRN gene. The gene was identified in 1996 and its product acts as a DNA helicase and exonuclease. Some specific WRN polymorphic variants were associated with increased risk for cardiovascular diseases. The identificatio...

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Source

Identifiers

PMID: 16007276
DOI: 10.1590/s0100-879x2005000700008

Genes

WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16007276-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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