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Article

WRN Cys1367Arg SNP is not associated with risk and prognosis of gliomas in Southeast Brazil.

Journal of neuro-oncology - 1 Dec 2008

Pinto Giovanny R, Yoshioka France K N, Clara Carlos A, Santos Marcelo J, Almeida José R W, Burbano Rommel R, Rey Juan A, Casartelli Cacilda

Abstract excerpt

Werner syndrome (WS) is a premature aging disorder characterized by early onset of symptoms related to normal aging and by a high predisposition to various types of cancer, including gliomas. WS is caused by inherited recessive mutations in the WRN gene, which encodes a helicase considered a caretaker of the genome. Aiming to study the role of WRN Cys1367Arg in glioma susceptibility and oncologic prognosis of...

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Identifiers

PMID: 18670736
DOI: 10.1007/s11060-008-9664-8

Genes

WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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WRN Cys1367Arg SNP is not associated with risk and prognosis of gliomas in Southeast Brazil.PMID 18670736Read ↗

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WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects.Semantic proximity Read ↗

The Werner's syndrome 4330T>C (Cys1367Arg) gene variant does not affect the in vitro cytotoxicity of topoisomerase inhibitors and platinum compounds.Semantic proximity Read ↗

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