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Article

A central role for the T1 domain in voltage-gated potassium channel formation and function.

The Journal of biological chemistry - 27 Jul 2001

Strang C, Cushman S J, DeRubeis D, Peterson D, Pfaffinger P J

Abstract excerpt

To interpret the recent atomic structures of the Kv (voltage-dependent potassium) channel T1 domain in a functional context, we must understand both how the T1 domain is integrated into the full-length functional channel protein and what functional roles the T1 domain governs. The T1 domain clearly plays a role in restricting Kv channel subunit heteromultimerization. However, the importance of T1 tetramerization...

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PMID: 11312262
DOI: 10.1074/jbc.M010540200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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