Article
Determinants of potassium channel assembly localised within the cytoplasmic C-terminal domain of Kv2.1.
Biochimica et biophysica acta - 14 Apr 1999
Bentley G N, Brooks M A, O'Neill C A, Findlay J B
Abstract excerpt
The C-terminal domain of the voltage-gated potassium channel Kv2.1 is shown to have a role in channel assembly using dominant negative experiments in Xenopus oocytes. Kv2.1 channel polypeptides were co-expressed with a number of polypeptide fragments of the cytosolic C-terminus and the assembly of functional channel homotetramers quantified electrophysiologically using the two electrode voltage clamp technique....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
