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Article

The high-resolution Structure of LeuB (Rv2995c) from Mycobacterium tuberculosis.

Journal of molecular biology - 11 Feb 2005

Singh Rajesh Kumar, Kefala Georgia, Janowski Robert, Mueller-Dieckmann Christoph, von Kries Jens-Peter, Weiss Manfred S

Abstract excerpt

The crystal structure of the enzyme 3-isopropylmalate dehydrogenase (IPMDH) from Mycobacterium tuberculosis (LeuB, Mtb-IPMDH, Rv2995c) without substrate or co-factor was determined at 1.65 A resolution, which is the highest resolution reported for an IPMDH to date. The crystals contain two functional dimers in the asymmetric unit in an arrangement close to a tetramer of D2 symmetry. Despite the absence of a...

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Identifiers

PMID: 15663922
DOI: 10.1016/j.jmb.2004.11.059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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