Article
A single nucleotide polymorphism on the promoter of eotaxin1 associates with its mRNA expression and asthma phenotypes.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2005
Chang Hun Soo, Kim Jung Sun, Lee June Hyuk, Cho Jung Il, Rhim Tai Youn, Uh Soo-Taek, Park Byung Lae, Chung Il Yup, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
Eotaxin1 plays a pivotal role in eosinophil-associated inflammation. Previously, we demonstrated 14 single-nucleotide polymorphisms (SNPs) in the human eotaxin1 gene and the association between the EOT+67G>A allele and the level of IgE. In this study, we investigated the association between the SNPs and plasma eotaxin1 levels, peripheral blood eosinophil counts, and PC20 methacholine values in normal and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
