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Article

Genetic interactions model among Eotaxin gene polymorphisms in asthma.

Journal of human genetics - 1 Jan 2008

Lee June-Hyuk, Moore Jason H, Park Sung-Woo, Jang An-Soo, Uh Soo-Taek, Kim Yong Hoon, Park Choon-Sik, Park Byung Lae, Shin Hyoung Doo

Abstract excerpt

Eotaxin family (Eotaxin 1,2 and 3) recruits and activates CCR3-bearing cells such as eosinophil, mast cells, and Th2 lymphocytes that play a major role in allergic disorders. We examined the polygenetic effects of the Eotaxin gene family in a Korean population. Gene-gene interactions were tested using a multistep approach with multifactor dimensionality reduction (MDR) method between asthmatics and normal...

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Identifiers

PMID: 18712274
DOI: 10.1007/s10038-008-0314-y

Genes

CCR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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