Article
Polymorphisms in interleukin 8 and its receptors (IL8, IL8RA and IL8RB) and association of common IL8 receptor variants with peripheral blood eosinophil counts.
Journal of human genetics - 1 Jan 2006
Cheong Hyun Sub, Shin Hyoung Doo, Lee Soo Ok, Park Byung Lae, Choi Yoo Hyun, Lim Gun Il, Uh Soo Taek, Kim Young Hun, Lee Jong-Young, Lee Jong-Keuk, Kim Hung Tae, Ryu Ha-Jung, Kim Ka-Kyung, Han Bok Ghee, Kim Jun Woo, Kimm Kuchan, Oh Bermseok, Park Choon-Sik
Abstract excerpt
Airway inflammation is a major factor in the pathogenesis of asthma. Interleukin 8 (IL8) is a potent proinflammatory cytokine that interacts with its receptors, IL8RA and IL8RB. We investigated the genetic polymorphisms in IL8, IL8RA, and IL8RB for any association with risk of asthma and peripher...
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