Article
Association of eotaxin-2 gene polymorphisms with plasma eotaxin-2 concentration.
Journal of human genetics - 1 Jan 2005
Min Ji-Won, Lee June-Hyuk, Park Choon-Sik, Chang Hun Soo, Rhim Tai Youn, Park Sung-Woo, Jang An-Soo, Shin Hyoung-Doo
Abstract excerpt
Chemokine (C-C motif) ligand 24 (CCL24, eotaxin-2) is a CC chemokine that recruits and activates cells bearing the CC chemokine receptor 3, which play a major role in asthma. Previously, we observed a significant association between a single nucleotide polymorphism (SNP) in eotaxin-2 (CCL24+1272A--> G) and a lower risk of asthma. Consequently, this study has followed up on those genetic effects by evaluating the...
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