Article
Mutational analysis of gene families in human cancer.
Current opinion in genetics & development - 1 Feb 2005
Bardelli Alberto, Velculescu Victor E
Abstract excerpt
The completion of the human genome project has marked a new beginning in biomedical sciences. Human cancer is a genetic disease and, accordingly, the field of oncology has been one of the first to be impacted by this historic revolution. Knowledge of the sequence and organization of the human genome facilitates the systematic analysis of the genetic alterations underlying the origin and evolution of tumors....
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