Article
High-throughput mutational analysis of the human cancer genome.
Pharmacogenomics - 1 Jun 2006
Ma Patrick C, Zhang Xiaodong, Wang Zhenghe J
Abstract excerpt
Cancer is essentially a genetic disease. Recent high-throughput mutational analyses of gene families in human colorectal, breast and lung cancer, myeloproliferative disorders, and other tumor types have identified a number of kinases and phosphatases that are mutated in the human cancer genome. This approach has been proven to be an efficient way to catalog tumor-specific mutations in human cancers. Although...
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