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Article

Tyrosine kinase mutations in human cancer.

Current molecular medicine - 1 Feb 2007

Lengyel Ernst, Sawada Kenjiro, Salgia Ravi

Abstract excerpt

A subset of tyrosine kinases are activated by mutations which contribute to the malignant transformation, growth, and metastasis of human cancers. Mutations change the expression, conformation and/or stability of tyrosine kinases, often leading to constitutive activation of the signaling pathways...

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Identifiers

PMID: 17311534
DOI: 10.2174/156652407779940486

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17311534-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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