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Article

Reactivation of Epstein-Barr virus can be triggered by an Rta protein mutated at the nuclear localization signal.

The Journal of general virology - 1 Feb 2005

Hsu Tsuey-Ying, Chang Yao, Wang Pei-Wen, Liu Mei-Ying, Chen Mei-Ru, Chen Jen-Yang, Tsai Ching-Hwa

Abstract excerpt

Rta, an immediate-early protein of Epstein-Barr virus (EBV), is a transcriptional activator that induces lytic gene expression and triggers virus reactivation. Being located predominantly in the nucleus, Rta can exert its transactivation function through either direct DNA binding or certain indirect mechanisms mediated by cellular signalling and other transcriptional factors. This study examined whether the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Herpesvirus 4, Human

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Identifiers

PMID: 15659750
DOI: 10.1099/vir.0.80556-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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