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Article

Induction of the Early Growth Response 1 Gene by Epstein-Barr Virus Lytic Transactivator Zta

13 Jul 2006

Abstract excerpt

Early growth response 1 (Egr-1) is a cellular transcription factor involved in diverse biologic functions. Egr-1 has been associated with Epstein-Barr virus (EBV) infection, but it is still unknown whether any EBV protein regulates Egr-1 expression. In this study, we first showed that EBV reactivation is involved in upregulation of Egr-1 and that Egr-1 can be induced by Zta, an EBV lytic transactivator. Zta not...

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Identifiers

PMID: 16840354
DOI: 10.1128/jvi.02608-05

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