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Article

Expression and regulation of the BKRF2, BKRF3 and BKRF4 genes of Epstein-Barr virus

7 Aug 2018

Abstract excerpt

The BKRF2, BKRF3 and BKRF4 genes of Epstein-Barr virus (EBV) are located close together in the viral genome, which encode glycoprotein L, uracil-DNA glycosylase and a tegument protein, respectively. Here, we demonstrate that the BKRF2 gene behaves as a true-late lytic gene, whereas the BKRF3 and BKRF4 genes belong to the early lytic gene family. Our results further reveal that both BKRF3 and BKRF4 promoters are...

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Identifiers

PMID: 30096410
DOI: 10.1016/j.virusres.2018.08.005

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