Article
Ubiquitin Modification of the Epstein-Barr Virus Immediate Early Transactivator Zta.
Journal of virology - 27 Oct 2020
Zhao Mengmeng, Nanbo Asuka, Becnel David, Qin Zhiqiang, Morris Gilbert F, Li Li, Lin Zhen
Abstract excerpt
The Epstein-Barr virus (EBV) immediate early transactivator Zta plays a key role in regulating the transition from latency to the lytic replication stages of EBV infection. Regulation of Zta is known to be controlled through a number of transcriptional and posttranscriptional events. Here, we show that Zta is targeted for ubiquitin modification and that this can occur in EBV-negative and in EBV-infected cells....
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