Article
PRA1 promotes the intracellular trafficking and NF-kappaB signaling of EBV latent membrane protein 1.
The EMBO journal - 6 Sept 2006
Liu Hao-Ping, Wu Chih-Ching, Chang Yu-Sun
Abstract excerpt
Latent membrane protein 1 (LMP1), which is an Epstein-Barr virus (EBV)-encoded oncoprotein, induces nuclear factor-kappa B (NF-kappaB) signaling by mimicking the tumor necrosis factor receptor (TNFR). LMP1 signals primarily from intracellular compartments in a ligand-independent manner. Here, we identify a new LMP1-interacting molecule, prenylated Rab acceptor 1 (PRA1), which interacts with LMP1 for the first...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
