Article
No influence of the P-glycoprotein polymorphisms MDR1 G2677T/A and C3435T on the virological and immunological response in treatment naïve HIV-positive patients.
Annals of clinical microbiology and antimicrobials - 20 Jan 2005
Winzer Ralf, Langmann Peter, Zilly Michael, Tollmann Franz, Schubert Jörg, Klinker Hartwig, Weissbrich Benedikt
Abstract excerpt
BACKGROUND: In a retrospective study of HIV-infected patients, we investigated the influence of the MDR1 genotype (G2677T/A and C3435T) on the virological and immunological response of treatment naive patients. METHODS: The MDR1 genotype was analysed from 72 patients in whom antiretroviral therapy was initiated between 1998 and 2004. Data were obtained at week 4, 12, 24 and 48 and were analysed by the...
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