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Article

Prevalence of MDR1 C3435T and CYP2B6 G516T polymorphisms among HIV-1 infected South African patients.

Disease markers - 1 Jan 2012

Masebe Tracy Madimabi, Bessong Pascal Obong, Nwobegahay Julius, Ndip Roland Ndip, Meyer Debra

Abstract excerpt

Data on genetic polymorphisms associated with response to anti-HIV drugs has accumulated over the years. Information on how polymorphisms influence drug metabolism and transport to target sites is important in guiding dosage or selection of appropriate alternative therapies. This study determined the frequency of MDR1 C3435T and CYP2B6 G516T polymorphisms associated with the transport and metabolism of efavirenz...

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Alkynes
ATP Binding Cassette Transporter, Subfamily B
Benzoxazines
Cyclopropanes
Cytochrome P-450 CYP2B6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxidoreductases, N-Demethylating

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Identifiers

PMID: 22297601
DOI: 10.3233/DMA-2012-0859
PMCID: PMC3826384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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