Article
No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment.
European journal of medical research - 9 Dec 2003
Winzer Ralf, Langmann P, Zilly M, Tollmann F, Schubert J, Klinker H, Weissbrich B
Abstract excerpt
BACKGROUND: In a retrospective study of HIV patients under antiretroviral therapy, we investigated the influence of the MDR1 genotype (C3435T) on plasma levels of lopinavir (LPV) and efavirenz (EFV). METHODS: The MDR1 genotype was analysed from 67 patients who were treated with LPV (n = 32; mean...
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