Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MDR1 3435T and 1236T alleles delay disease progression to pediatric AIDS but have no effect on HIV-1 vertical transmission.

AIDS (London, England) - 27 Mar 2010

Bellusci Carolina P, Rocco Carlos A, Aulicino Paula C, Mecikovsky Debora, Bologna Rosa, Sen Luisa, Mangano Andrea

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the MDR1 gene, coding for the drug transporter P-glycoprotein, may modulate the response to antiretroviral therapy and susceptibility to HIV-1 infection. We investigated whether the MDR1 SNPs C1236T (exon 12) and C3435T (exon 26) affect HIV-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Argentina
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to HIV Infections

Share to Infectious Disease Transmission, Vertical

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 20124970
DOI: 10.1097/QAD.0b013e328336abfc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20124970-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MDR1 3435T and 1236T alleles delay disease progression to pediatric AIDS but have no effect on HIV-1 vertical transmission.PMID 20124970Read ↗

Influence of MDR1 C1236T polymorphism on lopinavir plasma concentration and virological response in HIV-1-infected children.Semantic proximity Read ↗

An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children.Semantic proximity Read ↗

MDR1 C3435T and C1236T polymorphisms: association with high-risk childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

TRIM5α 136Q, CCR5 Promoter 59029G And CCR264I Alleles Impact The Progression Of HIV In Children And AdolescentsSemantic proximity Read ↗

MDR-1 gene polymorphisms and clinical course of steroid-responsive nephrotic syndrome in children.Semantic proximity Read ↗

The role of genetic variants of Stromal cell-Derived Factor 1 in pediatric HIV-1 infection and disease progression.Semantic proximity Read ↗

CCR2, CX3CR1, RANTES and SDF1 genetic polymorphisms influence HIV infection in a Zimbabwean pediatric population.Semantic proximity Read ↗

Evaluating the contribution of APOBEC3G haplotypes, on influencing HIV infection in a Zimbabwean paediatric population.Semantic proximity Read ↗

CCR2B-64I chemokine receptor allele and mother-to-child HIV-1 transmission or disease progression in children. French pediatric HIV infection study group.Semantic proximity Read ↗

Association between HLA-G 3'UTR 14-bp polymorphism and HIV vertical transmission in Brazilian children.Semantic proximity Read ↗

MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study.Semantic proximity Read ↗

No influence of the P-glycoprotein polymorphisms MDR1 G2677T/A and C3435T on the virological and immunological response in treatment naïve HIV-positive patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.