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Article

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study.

Lancet (London, England) - 5 Jan 2002

Fellay Jacques, Marzolini Catia, Meaden Emma R, Back David J, Buclin Thierry, Chave Jean Philippe, Decosterd Laurent A, Furrer Hansjakob, Opravil Milos, Pantaleo Giuseppe, Retelska Dorota, Ruiz Lidia, Schinkel Alfred H, Vernazza Pietro, Eap Chin B, Telenti Amalio

Abstract excerpt

BACKGROUND: HIV-1-infected patients vary considerably by their response to antiretroviral treatment, drug concentrations in plasma, toxic events, and rate of immune recovery. This variability could have a genetic basis. We did a pharmacogenetics study to analyse the association between response to antiretroviral treatment and allelic variants of several genes. METHODS: In 123 patients, we did PCR analyses of the...

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PMID: 11809184
DOI: 10.1016/S0140-6736(02)07276-8

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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