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Article

MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study.

Journal of acquired immune deficiency syndromes (1999) - 1 Nov 2003

Haas David W, Wu Hulin, Li Haihong, Bosch Ronald J, Lederman Michael M, Kuritzkes Daniel, Landay Alan, Connick Elizabeth, Benson Constance, Wilkinson Grant R, Kessler Harold, Kim Richard B

Abstract excerpt

Human CD4+ T cells express P-glycoprotein (P-gp), the ATP binding cassette efflux transporter encoded by MDR1. A common MDR1 single-nucleotide polymorphism in exon 26 (C3435T), which is linked to an exon 21 polymorphism (G2677T/A) and reportedly alters expression, has been associated with greater...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14600574
DOI: 10.1097/00126334-200311010-00006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14600574-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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