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Article

New tools for investigating macrophage differentiation.

Research in immunology - 1 Jan 1992

Ricciardi-Castagnoli P, Paglia P

Abstract excerpt

Mouse macrophage clones were generated from liver, bone marrow, spleen, thymus and brain by in vitro immortalization of primary cultures with VN11 recombinant retroviruses, transducing an avian v-myc oncogene. Tissue macrophages from eight different strains of mice were immortalized. All macrophage clones obtained thus far constitutively expressed F4/80, Mac-1, Mac-2 and Fc receptors. Class II MHC molecules were...

Topics

Animals
Cell Differentiation
Clone Cells
Genes, myc
Macrophage Activation
Macrophages
Mice
Mice, Inbred Strains
Models, Biological
Phenotype
Retroviridae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1565838
DOI: 10.1016/0923-2494(92)80086-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1565838-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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