Article
New tools for investigating macrophage differentiation.
Research in immunology - 1 Jan 1992
Ricciardi-Castagnoli P, Paglia P
Abstract excerpt
Mouse macrophage clones were generated from liver, bone marrow, spleen, thymus and brain by in vitro immortalization of primary cultures with VN11 recombinant retroviruses, transducing an avian v-myc oncogene. Tissue macrophages from eight different strains of mice were immortalized. All macrophage clones obtained thus far constitutively expressed F4/80, Mac-1, Mac-2 and Fc receptors. Class II MHC molecules were...
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