Article
Macrophage cell lines derived from major histocompatibility complex II-negative mice.
In vitro cellular & developmental biology. Animal - 1 Jun 1998
Beharka A A, Armstrong J W, Chapes S K
Abstract excerpt
Two bone-marrow-derived macrophage cell lines, C2D and C2Dt, were isolated from major histocompatibility class II negative knock-out mice. The C2D cell line was stabilized by continuous culture in colony-stimulating factor-1 and the C2Dt cell line was transformed with SV40 virus large T antigen. These cells exhibited phenotypic properties of macrophages including morphology and expression of Mac 1 and Mac 2 cell...
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