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Article

The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.

The Journal of biological chemistry - 1 Apr 2005

Li Lu, Li Zhigang, Sacks David B

Abstract excerpt

Estrogen binds to estrogen receptors in cells, thereby activating the receptors and eliciting biological effects. One of the best characterized effects of estrogen receptor-alpha (ERalpha) is transcriptional activation that regulates selected target genes in the nucleus. Work from several laboratories has documented a Ca2+-dependent interaction between ERalpha and calmodulin. In addition, we previously showed...

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PMID: 15657064
DOI: 10.1074/jbc.M410642200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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