Article
Requirements for estrogen receptor alpha membrane localization and function.
Steroids - 1 Jan 2000
Evinger Albert J, Levin Ellis R
Abstract excerpt
The estrogen receptor alpha (ERalpha) exists as a functional receptor at the plasma membrane. The structural requirements for localization and function are not well understood. Several laboratories have recently elucidated certain requirements. We recently found the translocation of ERalpha to the membrane in the absence of estrogen is dependent on caveolin-1 and serine 522 of the ERalpha protein. Mutation of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
