Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin.

Molecular and cellular biology - 1 Feb 2003

Antonsson Asa, Hughes Kate, Edin Sofia, Grundström Thomas

Abstract excerpt

The NF-kappa B/Rel family of transcription factors participates in the control of a wide array of genes, including genes involved in embryonic development and regulation of immune, inflammation, and stress responses. In most cells, inhibitory I kappa B proteins sequester NF-kappa B/Rel in the cytoplasm. Cellular stimulation results in the degradation of I kappa B and modification of NF-kappa B/Rel proteins,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calmodulin
Share to Granulocyte-Macrophage Colony-Stimulating Factor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to I-kappa B Proteins

Share to Interleukin-2

Share to Jurkat Cells

Share to Proto-Oncogene Proteins c-rel

Share to Tetradecanoylphorbol Acetate

Share to Transcription Factor RelA

Source

Open in PubMed Open full text

Identifiers

PMID: 12556500
DOI: 10.1128/MCB.23.4.1418-1427.2003
PMCID: PMC141150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin.PMID 12556500Read ↗

Kappa B site-dependent activation of the interleukin-2 receptor alpha-chain gene promoter by human c-Rel.Semantic proximity Read ↗

NF-κB c-Rel Dictates the Inflammatory Threshold by Acting as a Transcriptional RepressorSemantic proximity Read ↗

Calmodulin regulates Ca2+-sensing receptor-mediated Ca2+ signaling and its cell surface expression.Semantic proximity Read ↗

Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway.Semantic proximity Read ↗

Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven TranscriptionSemantic proximity Read ↗

CaMKII targets Bcl10 in T-cell receptor induced activation of NF-κB.Semantic proximity Read ↗

Identification and characterization of nuclear localization signals of CaMKP-N.Semantic proximity Read ↗

Regulation of phospholipase C-delta1 through direct interactions with the small GTPase Ral and calmodulin.Semantic proximity Read ↗

The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.Semantic proximity Read ↗

Calcium regulation of GM-CSF by calmodulin-dependent kinase II phosphorylation of Ets1.Semantic proximity Read ↗

Nucleolar sequestration of RelA (p65) regulates NF-kappaB-driven transcription and apoptosis.Semantic proximity Read ↗

CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.