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Article

Ligand-independent activation of oestrogen receptor alpha by caveolin-1.

The Biochemical journal - 1 Oct 2001

Schlegel A, Wang C, Pestell R G, Lisanti M P

Abstract excerpt

Expression of caveolin-1 in the human mammary adenocarcinoma cell line MCF-7 causes ligand-independent concentration of oestrogen receptor alpha (ERalpha) in the nucleus, and potentiates ligand-independent and ligand-dependent transcription from an oestrogen response element-driven reporter gene. Furthermore, caveolin-1 co-immunoprecipitates with ERalpha [Schlegel, Wang, Katzenellenbogen, Pestell and Lisanti...

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Source

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Identifiers

PMID: 11563984
DOI: 10.1042/0264-6021:3590203
PMCID: PMC1222136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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