Article
Effect of 3'UTR length on the translational regulation of 5'-terminal oligopyrimidine mRNAs.
Gene - 3 Jan 2005
Ledda Mario, Di Croce Mara, Bedini Barbara, Wannenes Francesca, Corvaro Marco, Boyl Pietro Pilo, Caldarola Sara, Loreni Fabrizio, Amaldi Francesco
Abstract excerpt
In Vertebrates, all genes coding for ribosomal proteins, as well as those for other proteins implicated in the production and function of translation machinery, are regulated by mitogenic and nutritional stimuli, at the translational level. A cis-regulatory element necessary for this regulation is the typical 5'UTR, common to all ribosomal protein mRNAs, which always starts at the 5' end with several pyrimidines....
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