Article

Flexibility and modulation of translation initiation in enterovirus genomes

2025-03-24

Abstract excerpt

Enteroviruses comprise a large group of mammalian pathogens that often utilize two open reading frames (ORFs) to encode their proteins: the upstream protein (UP) and the main polyprotein. In some enteroviruses, in addition to the canonical upstream AUG (uAUG), there is another AUG that may represent an alternative upstream initiation site. An analysis of enterovirus sequences containing additional upstream AUGs id...

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Literature Corpus work: 527a6fe2-dffb-55ff-9d03-033020ef0949
DOI: 10.1101/2025.03.24.645098

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