Article
Design of 5'-untranslated region variants for tunable expression in Escherichia coli.
Biochemical and biophysical research communications - 27 Apr 2007
Park Young Seoub, Seo Sang Woo, Hwang Seungha, Chu Hun Su, Ahn Jin-Ho, Kim Tae-Wan, Kim Dong-Myung, Jung Gyoo Yeol
Abstract excerpt
Redesign or modification of the cellular physiology requires a quantitatively well-controlled expression system known as the "tunable expression." Although the modification of promoters demonstrates the great impact on the translation efficiency, it is difficult to detect the proper variants required for tunable expression. The 5'-untranslated region (UTR), however, can be an important target for tunable...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.