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Article

A motif in the 5'untranslated region of messenger RNAs regulates protein synthesis in a S6 kinase-dependent manner.

Advances in biological regulation - 1 Aug 2023

Shin Hyun-Chul, Bochkov Yury A, Kim Kangsan, Gern James E, Jarjour Nizar N, Esnault Stephane

Abstract excerpt

The 5' untranslated regions (UTRs) in messenger RNAs (mRNAs) play an important role in the regulation of protein synthesis. We had previously identified a group of mRNAs that includes human semaphorin 7A (SEMA7A) whose translation is upregulated by the Erk/p90S6K pathway in human eosinophils, with a potential negative impact in asthma and airway inflammation. In the current study, we aimed to find a common 5'UTR...

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Identifiers

PMID: 37302177
DOI: 10.1016/j.jbior.2023.100975
PMCID: PMC10735251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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