Article
Activity of adefovir dipivoxil against all patterns of lamivudine-resistant hepatitis B viruses in patients.
Journal of viral hepatitis - 1 Jan 2005
Westland C E, Yang H, Delaney W E, Wulfsohn M, Lama N, Gibbs C S, Miller M D, Fry J, Brosgart C L, Schiff E R, Xiong S
Abstract excerpt
One hundred and thirty-one post-liver transplantation patients with chronic hepatitis B and failing lamivudine therapy with detectable serum hepatitis B virus (HBV) deoxyribonucleic acid by hybridization assays or > or =1 x 10(6) copies/mL by polymerase chain reaction, and elevated alanine transaminase levels despite continuous lamivudine, were enrolled in an open-label study of adefovir dipivoxil. The B and C...
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